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Results for "
spadin acetate
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Peptide Products1
Spadin Acetate
Spadin Acetate(1270083-24-3 Free base)
T22178L
Spadin Acetate is a natural peptide derived from a propeptide released in blood. Spadin Acetate is able to block the TREK-1 channel activity. Spadin Acetate binds specifically to TREK-1 with an affinity of 10 nM.
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T75944
Spadin TFA, a natural peptide originating from a propeptide in blood, acts as a powerful TREK-1 channel inhibitor with an IC 50 of 10 nM. It boosts dorsal raphe nucleus 5-HT neurotransmission in mice, activates hippocampal CREB, and promotes neurogenesis. This compound is useful for antidepressant research [1] [2].
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