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(2)
By Target- JNK
- Apoptosis(1)
- Aurora Kinase(1)
- Autophagy(1)
- Ferroptosis(1)
- Trk receptor(1)
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Results for "
sp-600125
" in TargetMol Product Catalog- Inhibitors & Agonists2
SP600125
Pyrazolanthrone, Nsc75890, JNK Inhibitor II, 1PMV
T3109129-56-6
SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40 40 90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
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SP 600125, negative control
JNK Inhibitor II, negative control
T3826054642-23-8
SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45β MKK7 (growth arrest and DNA damage-inducible β mediator-activated protein kinase kinase kinase 7) and is capable of restoring activation.The IC50s of SP 600125, negative control against JNK2 and JNK3 were 18 and 24 μM, respectively.
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