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By Target- Akt
- Apoptosis(1)
- Caspase(1)
- JNK(1)
- MAPK(1)
- Rho(1)
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By Target By ResearchField- Cancer(1)
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Results for "
sklb-163
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- SKLB-163SKLB163T261931255099-06-9In houseSKLB-163 is a small-molecule inhibitor and a RhoGDI inhibitor with oral bioactivity, cell permeability, and selectivity. This compound induces tumor cell apoptosis, inhibits proliferation and migration, and enhances radiosensitivity by downregulating RhoGDI, activating the JNK-1/caspase-3 pathway, and suppressing Akt and p44/42 MAPK phosphorylation.
- $137
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