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(1)
By Target- Bcr-Abl
- Ligand for E3 Ligase(1)
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Results for "
siais-178
" in TargetMol Product Catalog- Inhibitors & Agonists1
- PROTAC Products1
SIAIS178
SIAI S178
T129072376047-73-1
SIAIS178 is a selective PROTAC degrader targeting BCR-ABL with an IC50 of 24 nM. It degrades BCR-ABL protein by recruiting the VHL E3 ubiquitin ligase, inhibiting leukaemia cell growth in vitro and causing regression of K562 xenograft tumours.
- $163
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