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(2)
By Target- Phosphatase
- ERK(1)
- Others(1)
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Results for "
shp099
" in TargetMol Product Catalog.- Inhibitors & Agonists3
SHP099
Cited
SHP099 free base, SHP-099, SHP 099
T35641801747-42-1
SHP099 is an oral, highly selective, allosteric SHP2 (PTPN11) inhibitor with an IC₅₀ of 70 nM. SHP099 inhibits tumor cell proliferation and survival by stabilizing the autoinhibitory conformation of SHP2 and blocking RAS-ERK signaling. SHP099 inhibits the growth of cancer cells, such as MV4-11 and TF-1 cells (IC₅₀ = 0.32 and 1.73 μM). SHP099 can be used in tumor research.
- $31
Size
QTY
CitedSHP099 hydrochloride Cited
T35442200214-93-1
SHP099 hydrochloride is a potent, selective, orally bioavailable SHP2 inhibitor with IC50 of 70 nM, which inhibits ERK1/2 activation in cancer cells. [2]
- $32
Size
QTY
CitedSHP099 HCl
T67211
SHP099 HCl is a useful organic compound for research related to life sciences and the catalog number is T67211.
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