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Results for "
sch 42495
" in TargetMol Product Catalog- Inhibitors & Agonists4
(R)-SCH 42495
T12641156792-25-5
(R)-SCH 42495, the less active enantiomer of SCH 42495, is an orally active inhibitor of neutral metalloendopeptidase (NEP) with antihypertensive effects.
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SCH 42495 racemate
SCH 42495 (racemate)
T12866145841-10-7
SCH 42495 racemate is the racemate of SCH 42495, an orally active neutral inhibitor of metalloendopeptidase (NEP) with antihypertensive effects.
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SCH-42354
T61095144505-58-8
SCH-42354 is a potent, orally active inhibitor of neutral endopeptidase (NEP), serving as the active form of the prodrug SCH-42495. By inhibiting NEP hydrolysis, SCH-42354 enhances the activity of atrial natriuretic peptide (ANP) and prevents the hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. Furthermore, SCH-42354 exhibits antihypertensive activity [1] [2].
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