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sc144

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  • Inhibitors & Agonists
    5
    TargetMol | All_Pathways
SC144
T6207895158-95-9
SC144 is an orally active small-molecule gp130 inhibitor.
  • $39
In Stock
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TargetMol | Citations Cited
SC144 hydrochloride
T41260917497-70-2
SC144 hydrochloride, a first-in-class, orally active, small-molecule gp130 (IL6-beta) inhibitor, demonstrates potent inhibition of gp130 ligand-triggered signaling. By binding to gp130, it initiates gp130 phosphorylation (S782) and deglycosylation, impedes Stat3 phosphorylation and nuclear translocation, and suppresses the expression of downstream target genes. Furthermore, SC144 hydrochloride effectively induces apoptosis in human ovarian cancer cells [1].
  • $53
5 days
Size
QTY
Ubiquitin Isopeptidase Inhibitor I, G5
NSC144303
T17192108477-18-5In house
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
  • $74
In Stock
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NSC 144698
NSC-144698, NSC144698
T33738136242-91-6
NSC 144698 is a bioactive chemical.
  • Inquiry Price
3-6 months
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Erioflorin
T6952727542-17-2
Erioflorin is an ATP-competitive selective c-Jun N-terminal kinase (JNK) inhibitor.
  • Inquiry Price
6-8 weeks
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QTY