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(2)
By Target- ALK
- Autophagy(2)
- TGF-beta/Smad(2)
- Apoptosis(1)
- MEK(1)
- PARP(1)
- Wnt/beta-catenin(1)
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Results for "
sb431542
" in TargetMol Product Catalog- Inhibitors & Agonists4
SB-431542
SB 431542
T1726301836-41-9
SB-431542 is an inhibitor of ALK5 TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells.
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Mirdametinib
PD325901, PD0325901
T6189391210-10-9
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1 2 expression and inducing apoptosis.
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XAV-939
XAV939, NVP-XAV939
T1878284028-89-3
XAV-939 (NVP-XAV939) is a Tankyrase (TNKS) inhibitor that inhibits TNKS1 and TNKS2 (IC50=11 4 nM). XAV-939 selectively inhibits Wnt β-catenin-mediated transcription.
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