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Results for "
sb-206553 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists1
SB 206553 hydrochloride
SB206553 hydrochloride
T233141197334-04-5
SB 206553 hydrochloride is an orally active, selective, and efficient 5-HT2C inverse agonist and 5-HT2C 5-HT2B receptor antagonist with anti-anxiety activity. It is useful in neurological disease research.
- $52
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5-HT 2C Serotonin Receptor Antagonist, SB 206553, 5-HT 2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553
T87364158942-04-2
SB 206553 is a 5-HT2C inverse agonist that can attenuate methamphetamine-seeking behavior in rats. It exhibits activity for 5-HT2 receptor ligands with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B), and 7.8 nM (5-HT2C) in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors. SB 206553 can be used for research into psychostimulant abuse disorders [1].
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