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sar405838

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
SAR405838
MI-77301, MI-773, MI773, MI 773
T65851303607-60-4In house
MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
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MI-773
MI773, MI 773
T639741303607-07-9
MI-773 is a potent inhibitor of MDM2-p53 protein-protein interaction (PPI), showing high binding affinity to MDM2 (Kd=8.2 nM) and antitumor activity.
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