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s1230

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Flavopiridol
NSC 649890 HCl, L868275, HMR-1275, Alvocidib
T6837146426-40-6
Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1 2.
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Pinacidil
S 1230, P 1134, S-1230, P-1134, P1134
T12478L60560-33-0
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.
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4-6 weeks
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