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ruski43

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  • Inhibitors & Agonists
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RU-SKI 43
RUSKI 43
T127971043797-53-0In house
RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
  • $118
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RU-SKI 43 Hydrochloride
RU-SKI43 Hydrochloride
T12797L1782573-67-4
RU-SKI 43 Hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat), with an IC50 value of 850 nM. RU-SKI 43 Hydrochloride has been reported to possess anticancer activity, making it a useful compound for investigating Hedgehog signaling in tumor biology.
  • $73
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