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(2)
By Target- Acyltransferase
- Hedgehog/Smoothened(2)
- Others(1)
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By Target By ResearchField- Cancer(2)
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Results for "
ruski-43
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- RU-SKI 43RUSKI 43T127971043797-53-0In houseRU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
- $45
SizeQTY - RU-SKI 43 HydrochlorideRU-SKI43 HydrochlorideT12797L1782573-67-4RU-SKI 43 Hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat), with an IC50 value of 850 nM. RU-SKI 43 Hydrochloride has been reported to possess anticancer activity, making it a useful compound for investigating Hedgehog signaling in tumor biology.
- $69
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