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Results for "
rp 6306
" in TargetMol Product Catalog- Inhibitors & Agonists2
(R)-Lunresertib
(R)-RP-6306, (R)-RP6306
T608862719793-91-4
(R)-Lunresertib is the enantiomer of the PKMYT1 inhibitor RP-6306, which negatively regulates CDK1 via phosphorylation of threonine 14 and cytoplasmic sequestration. (R)-Lunresertib demonstrates single-agent antitumor efficacy in CCNE1-amplified xenograft models and shows synergistic effects with gemcitabine in CCNE1-amplified or overexpressing cell lines, providing a critical tool in cancer pharmacology and precision oncology research.
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