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  • E1/E2/E3 Enzyme
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  • BMI-1
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ring1a

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
PRT4165
NSC600157, PRT 4165
T311031083-55-3
PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.
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PRC1-IN-1
T2053062396639-29-3
PRC1-IN-1 (compound RB-4) is an inhibitor of the polycomb repressive complex 1 (PRC1) with an IC50 of 2.3 μM. It targets RING1B-BMI1, RING1A-BMI1, and RING1B-PCGF1, exhibiting IC50 values of 2.8 μM, 2.6 μM, and 1.8 μM, respectively.
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10-14 weeks
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