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By Target- Apoptosis
- Autophagy(1)
- FLT(1)
- Ligands for Target Protein for PROTAC(1)
- PLK(1)
- Others(2)
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Results for "
quizartinib
" in TargetMol Product Catalog- Inhibitors & Agonists4
- PROTAC Products2
Quizartinib
AC220
T2066950769-58-1
Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
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Desmorpholinyl Quizartinib-PEG2-COOH
Desmorpholinyl Quizartinib-PEG2-COOH
T398182292116-14-2
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
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