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psychomotor seizures

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
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    TargetMol | Recombinant_Protein
2-(Isopentylamino)naphthalene-1,4-dione
T379501607447-79-9
2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively). 1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential treatment of pharmacoresistant seizuresJ. Med. Chem.63(11)5865-5878(2020)
  • TBD
35 days
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Pheneturide
S-46, Benuride, 2-PHENYLBUTYRYLUREA
T859490-49-3
Pheneturide (Benuride) is the ureide class, used to treat epilepsy, and is an anticonvulsant.
  • $41
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