Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Protease-activated Receptor
    (38)
  • Apoptosis
    (1)
  • Calcium Channel
    (1)
  • ERK
    (1)
  • Proteasome
    (1)
Filter
Search Result
Results for "

proteaseactivated receptor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    41
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    23
    TargetMol | Peptide_Products
  • Inhibitory Antibodies
    1
    TargetMol | Inhibitory_Antibodies
  • Natural Products
    1
    TargetMol | Natural_Products
BMS-986141
UDM-003183
T639661478711-48-6In house
BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibits significant antithrombotic effects.
  • Inquiry Price
10-14 weeks
Size
QTY
atopaxar hydrobromide
T1986L474550-69-1
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
  • Inquiry Price
6-8 weeks
Size
QTY
TargetMol | Citations Cited
Vorapaxar
SCH 530348, MK-5348
T7013618385-01-6
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).
  • Inquiry Price
Size
QTY
TargetMol | Citations Cited
TRAP-6
Thrombin Receptor Activator Peptide 6, PAR-1 agonist peptide
T7625141136-83-6
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
iso-TRAP-6
iso-SFLLRN
T78099150242-29-8
iso-TRAP-6 (iso-SFLLRN), a hexapeptide derived from the substitution of isoserine for serine, is a protease-activated receptor 1 (PAR1) agonist that activates platelets via PAR-1. iso-TRAP-6 is more resistant to degradation by plasma aminopeptidases than iso-TRAP-6.
  • Inquiry Price
8-10 weeks
Size
QTY
PAR-2 Activating Peptide acetate
SLIGRL-NH2 acetate, Protease-Activated Receptor-2 Activating Peptide acetate, PAR-2 Activating Peptide acetate(171436-38-7 free base)
TP1046L
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
  • Inquiry Price
Size
QTY
Atopaxar
E5555, ER-172594-00
T1986751475-53-3In house
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
  • Inquiry Price
6-8 weeks
Size
QTY
AY 77
Unk-Cha-Chg-NH2
T411901835734-92-3In house
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1 2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1 2 phosphorylation was 2 μM). AY 77 can promote migration of human breast cancer cells in vitro.
  • Inquiry Price
8-10 weeks
Size
QTY
TargetMol | Inhibitor Sale
Trypsin
TN68729002-07-7
Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cells through the interaction between the S glycoprotein of PDCoV and pAPN, activate PAR2 and PAR4, and promote cell proliferation and differentiation. Trypsin can be used to promote wound healing and study neurogenic inflammation.
  • Inquiry Price
7-10 days
Size
QTY
Parmodulin 2
ML 161
T1893423735-93-7
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thrombin-induced platelet activation.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
TargetMol | Citations Cited
TFLLR-NH2 2TFA(197794-83-5(free base))
T7573L
TFLLR-NH2 2TFA(197794-83-5(free base)) is an agonist of PAR1 (EC50 :1.9 μM).
  • Inquiry Price
Size
QTY
TargetMol | Citations Cited
SCH79797 dihydrochloride
T128701216720-69-2
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects.
  • Inquiry Price
6-8 weeks
Size
QTY
TargetMol | Inhibitor Sale
LRGILS-NH2 acetate
T22933L
LRGILS-NH2 acetate is a PAR-2-inactive reversed peptide.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
AC-55541
AOB2796
T2370916170-19-9
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
TRAP-6 amide acetate
T38852L
TRAP-6 amide acetate is a PAR-1 thrombin receptor agonist peptide[1].
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Thrombin Receptor Activator for Peptide
T7674
Thrombin Receptor Activator for Peptide is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
VKGILS-NH2 Acetate
VKGILS-NH2 Acetate (942413-05-0 Free base)
T21699L
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.
  • Inquiry Price
Size
QTY
ML-354
VU 0099704, ML354, VU0099704
T2190189159-60-4
ML-354 (VU0099704) is a selective and potent PAR4 antagonist for the study of cardiovascular disease.
  • Inquiry Price
6-8 weeks
Size
QTY
ENMD-1068 HCl
ENMD-1068 HCl, ENMD 1068, ENMD-1068, ENMD1068, ENMD-1068 hydrochloride
T27267789488-77-3
ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.
  • Inquiry Price
6-8 weeks
Size
QTY
Vorapaxar sulfate
SCH 530348 sulfate, Zontivity, vorapaxar monosulfate
T3098705260-08-8
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.
  • Inquiry Price
Size
QTY
Protease-Activated Receptor-3 (PAR-3) (1-6), human
T362861872435-09-0
TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.
  • Inquiry Price
Size
QTY
Protease-Activated Receptor-1, PAR-1 Agonist TFA
T36288
Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the actions of thrombin through the PAR-1 receptor[1][2].
  • Inquiry Price
Size
QTY
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
T36289
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA, is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3) [1].
  • Inquiry Price
Size
QTY
Protease-Activated Receptor-1, PAR-1 Agonist
T38836141136-85-8
Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activation of this receptor.
  • Inquiry Price
Size
QTY