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ppads

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
PPADS
T89112149017-66-3
PPADS is a P2 receptor antagonist with IC50 values of 68 nM (P2X1) and 214 nM (P2X3). This compound functions as an ATP (nucleotide) analog, competing for binding sites on the P2 receptors with ATP. Additionally, PPADS acts as a reversible competitive antagonist of the NAADP receptor. It is capable of reversing hyperalgesia, and it diminishes the enhanced NO NOS signaling and IL-1β production in both peripheral and central steps of the nervous system.
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10-14 weeks
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PPADS tetrasodium
T16564192575-19-2
PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate NMDA toxicity.PPADS tetrasodiuma inhibits P2X1, P2X-2, P2X-3, and P2X- 5. 5.
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7-10 days
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