Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Apoptosis
    (1)
  • Chk
    (1)
  • IGF-1R
    (1)
  • Others
    (1)
Filter
Search Result
Results for "

podophyllum peltatum

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
  • Natural Products
    4
    TargetMol | Natural_Products
4'-Demethylpodophyllotoxin
T2S002940505-27-9
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
  • Inquiry Price
Size
QTY
Picropodophyllotoxin
Picropodophyllin, AXL 1717
T3S002717434-18-3
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential antineoplastic activity. Picropodophyllotoxin (AXL 1717) specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast stem cell growth factor (KIT). This agent shows potent activity in the suppression o f tumor cell proliferation and the induction of tumor cell apoptosis. IGF1R, a receptor tyrosine kinase overexpressed in a variety of human cancers, plays a critical role in the growth and survival of many types of cancer cells.
  • Inquiry Price
Size
QTY
4-Demethyldeoxypodophyllotoxin
T833213590-93-0
4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.
  • Inquiry Price
Size
QTY
(-)-Epipodophyllotoxin
TN70414375-07-9
(-)-Epipodophyllotoxin (2) is an antiproliferative agent targeting cancer cells, exhibiting GI50 values of 0.36 μM in HeLa cells and 0.24 μM in MCF-7 cells, and inhibiting mitotic spindle assembly in vitro.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale