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pmel 17

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  • Recombinant Protein
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    TargetMol | Recombinant_Protein
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Osteoactivin/GPNMB Protein, Human, Recombinant (aa 22-486, His)
Transmembrane Glycoprotein NMB, Transmembrane Glycoprotein HGFIN, NMB, HGFIN, GPNMB
TMPJ-01119
Osteoactivin is an intracellular glycoprotein belongs to the NMB pMEL-17 family, which is asscociated with cell endosomal lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages keratinocytes.
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7-10 days
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SPR-compatible buffer