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Anti-PMEL Monoclonal Antibody (5L288)
(Synonyms: SILV, SIL, SI, PMEL17, P100, P1, ME20-M, ME20M, ME20, gp100, D12S53E) Copy Product Info
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Synonyms: SILV, SIL, SI, PMEL17, P100, P1, ME20-M, ME20M, ME20, gp100, D12S53E
Catalog No. TMAT-1015 Copy Product Info
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Anti-PMEL Monoclonal Antibody (5L288) is a Mouse antibody targeting PMEL. Anti-PMEL Monoclonal Antibody (5L288) can be used in FCM.
Anti-PMEL Monoclonal Antibody
(5L288)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-PMEL Monoclonal Antibody (5L288) is a Mouse antibody targeting PMEL. Anti-PMEL Monoclonal Antibody (5L288) can be used in FCM. |
| Synonyms | SILV, SIL, SI, PMEL17, P100, P1, ME20-M, ME20M, ME20, gp100, D12S53E |
| Ig Type | IgG1 |
| Clone | 5L288 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PMEL (AA: 25-192) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PMEL |
| Gene ID | |
| Protein Name | Melanocyte protein PMEL |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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