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(2)
By Target- Ferroptosis
- MDM-2/p53(2)
- p53(2)
- Apoptosis(1)
- Aryl Hydrocarbon Receptor(1)
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By Target By ResearchField- Cancer(2)
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Results for "
pifithrinα hydrobromide
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Pifithrin-α hydrobromidePifithrin-α (PFTα) HBr, Pifithrin-α, Pifithrin hydrobromide, PFTα hydrobromide, PFTαT270763208-82-2Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.
- $33
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Cited - Pifithrin-β hydrobromidePifithrin-β, PFT-β, PFT β (hydrobromide), Cyclic Pifithrin-α hydrobromide, Cyclic PFT-αT3637511296-88-1Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM).
- $34
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