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pi-3kα-in-4

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
PI3Kα-IN-4
PI3Kα-IN-4
T355272322293-83-2
PI3Kα-IN-4 is a potent, selective, and orally active PI3Kα inhibitor with an IC50 of 1.8 nM, demonstrating antitumor activity [1].
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6-8 weeks
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(S)-PI3Kα-IN-4
(S)-PI3Kα-IN-4
T354882322293-84-3
(S)-PI3Kα-IN-4, a potent inhibitor of PI3Kα with an IC50 of 2.3 nM, demonstrates 38.3-, 4.25-, and 4.93-fold selectivity over PI3Kβ, PI3Kδ, and PI3Kγ, respectively, and is suitable for cancer research[1]. (S)-PI3Kα-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution[1].
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6-8 weeks
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