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By Target- Na-K-Cl cotransporter
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Results for "
pf1593
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- BumetanideRo 10-6338, PF 1593T010828395-03-1Bumetanide (PF 1593) is a potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by blocking the bumetanide-sensitive sodium-potassium-chloride cotransporter (NKCC1), thereby inhibiting chloride uptake thus, decreasing the internal chloride concentration in neurons and may block the excitatory effect of GABA in neonates.
- $64
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Other Forms of Products
- Bumetanide-D5
T106331216739-35-3Bumetanide-D5 is a deuterium-labeled Bumetanide. Bumetanide (T0108) is a Na+-K+-Cl- (NKCC1) inhibitor (IC50s: 0.68 and 4.0 μM for hNKCC1A and hNKCC2A).- $230
SizeQTY - Bumetanide sodiumT6171328434-74-4Bumetanide sodium is a potent loop diuretic that acts as a blocker for the sodium-potassium-chloride cotransporter (NKCC). It selectively inhibits NKCC1 and NKCC2, with IC50 values of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively [1] [2].Inquiry
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