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(2)
By Target- ALK
- Apoptosis(2)
- ROS Kinase(2)
- ROS(1)
- Tyrosine Kinases(1)
- Others(1)
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By Target By ResearchField- Cancer(1)
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Results for "
pf06463922
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- LorlatinibPF-6463922, PF-06463922, LoratinibT30611454846-35-5Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.
- $30
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Cited - PF-06463922 acetateT700601924207-18-0PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).
- $2,420
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