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Results for "
pf-6274484
" in TargetMol Product Catalog- Inhibitors & Agonists1
pf-6274484
PF 6274484
T223961035638-91-5
PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively.
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