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p80 tnf-a receptor

" in TargetMol Product Catalog
  • Recombinant Protein
    3
    TargetMol | Recombinant_Protein
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TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)
TNFRSF1B, TNFR80, TNF-R75, TNF-R2, TNFR2, TNFR1B, TNFBR, TNF RII, TBPII, p75TNFR, p75TBPII, Etanercept, CD120b
TMPK-01382
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75 p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2 TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1 lymphotoxin-alpha. The TRAF1 TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer