p 165

Azaserine (CI-337) is a tumor-inhibiting antibiotic isolated from a species of Streptomyces and functions as an inhibitor of glutamine amidotransferase.

Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias, and angina research.

IMAB027 (ASP1650) is a selective monoclonal antibody against CLDN6 (Claudin 6) with antitumor activity that induces death of CLDN6+ cancer cells through antibody-dependent and complement-dependent cytotoxicity.

Myelin Basic Protein (MBP 4-14) is a protein believed to be important in the process of myelination of nerves in the nervous system.

Proinsulin C-peptide (human) is a 31-amino acid peptide that links the Proinsulin A and B chains, ensuring their proper folding, biological activity, and regulation of cellular functions.

Proinsulin C-peptide human acetate (Proinsulin C-peptide human acetate (33017-11-7 Free base)) is a polypeptide of 31 amino acid residues that links the A and B chains of proinsulin to ensure proper folding, has biological activity and regulates cellular functions.

OVA G4 peptide TFA is an TFA salt form of OVA G4 peptide. G4 peptide (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).

This peptide, a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus.

SV40 T-Ag-derived NLS peptide acetate (SV40 T-Ag-derived NLS peptide acetate) is a nuclear localization signal peptide. The DNA labeled with this peptide can be effectively transferred to the nucleus.

H-Ala-Ala-Tyr-OH TFA can be synthesized mutant peptides.

Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)

VIR-165 is a modified form of virus inhibitory peptide (VIRIP), corresponding to residues 353 to 372 of the C-proximal region of human alpha1-antitrypsin, the most abundant circulating serine protease inhibitor. VIRIP inhibits a wide variety of human immunodeficiency virus type 1 (HIV-1) strains.

Type A Allatostatin I, a tridecapeptide, belongs to the category of pleiotropic neuropeptides known for their ability to inhibit the synthesis of juvenile hormone in insects.

Type A Allatostatin I acetate is a tridecapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.

Lactoferrin (17-41) TFA (146897-68-9 free base) is amino acids 17 to 41 fragment of lactoferrin, known as lactoferricin B. Lactoferrin (17-41) TFA (146897-68-9 free base) shows anti-fungal properties in combination of other anti-fungal agents.Candida Albicans is one of the targets of the lactoferricin B.

HDAC-IN-88 (Compound HJ-9) is a potent inhibitor of HDAC, effectively targeting HDAC6, HDAC1, HDAC2, HDAC8, and HDAC3 with IC50 values of 0.226, 1.103, 2.308, 3.255, and 3.864 μM, respectively. This compound suppresses the proliferation of cancer cells HepG2, HCT116, and MV4-11 with IC50 values of 5.47, 9.78, and 0.38 μM, respectively. Additionally, it inhibits the migration of HCT116 cells, causes cell cycle arrest at the G0/G1 phase, and induces apoptosis and autophagy in MV4-11 cells. HDAC-IN-88 reduces ROS levels and mitochondrial membrane potential and demonstrates antimalarial activity by inhibiting Plasmodium falciparum 3D7 with an EC50 of 165 nM. Furthermore, HDAC-IN-88 exhibits anti-angiogenic properties.