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(1)
By Target- EBI2/GPR183
- Endogenous Metabolite(1)
- Others(2)
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oxysterols
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7α,25-Dihydroxycholesterol
7α,25-OHC
T1406364907-22-8
7α,25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist, as well as an endogenous ligand, of the orphan GPCR receptor EBI2 (GPR183). It serves as a chemokine directing the migration of B cells, T cells, and dendritic cells and exhibits high potency in activating EBI2 (EC50=140 pM; Kd=450 pM) [1][2].
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