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ory1001

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
ORY1001
RG-6016, ORY-1001, ORY 1001
T69221431326-61-2
ORY1001 (ORY 1001) is an orally active and selective lysine-specific demethylase LSD1 KDM1A inhibitor, with high selectivity against related FAD dependent aminoxidases with IC50 of <20 nM.
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ORY-1001 free base
RG 6016,ORY-1001,ORY 1001,ORY1001,RG-6016,RG6016
T282691431304-21-0
ORY-1001 is a KDM1A inhibitor (IC50 <20nM) with high selectivity against related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B >100uM, SMOX 7uM). Treatment of THP-1 (MLL-AF9) cells with ORY-1001, results in a time/dose dependent me2H3K4 accumulation a
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6-8 weeks
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Iadademstat dihydrochloride
ORY-1001(trans)
T58251431303-72-8
Iadademstat dihydrochloride (ORY-1001(trans)) , a Potent and Selective Covalent KDM1A LSD1 Inhibitor, for the Treatment of Acute Leukemia.
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