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  • OX Receptor
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Results for "

orexin receptor antagonist 2

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    11
    TargetMol | Inhibitors_Agonists
Orexin receptor antagonist 2
T381391457940-75-8
Orexin Receptor Antagonist 2 (compound 30), characterized by its potent antagonistic activity with pKis of 7.69 and 9.78, holds promise for insomnia research[1].
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6-8 weeks
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Seltorexant
JNJ-42847922
T12877L1293281-49-8
Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).
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MK-3697
T19131224846-01-8
MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
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Almorexant
ACT 078573
T2613871224-64-5
Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1) orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
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TargetMol | Inhibitor Sale
ACT-462206
T265591361321-96-1
ACT-462206 is an orally available Orexin 1 Orexin 2 receptor antagonist that crosses the blood-brain barrier.ACT-462206 is highly potent and can be used in studies of sleep and anxiety.
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7-10 days
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MK-8133
T280601431472-56-8
MK-8133 is an antagonist of orexin-2 selective receptor with favorable development properties.
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6-8 weeks
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MK-1064
Urokinase inhibitor 1, MK 1064
T37221207253-08-4
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
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TCS-OX2-29 HCl
TCSOX 229,TCS-OX229,TCS OX229,TCS OX2 29,TCSOX-229,TCSOX229
T4965L1610882-30-8
TCS-OX2-29 is a selective orexin-2 receptor antagonist (IC50 = 40 nM), which plays an important role in pain modulation.
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1-2 weeks
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orexin receptor antagonist 4
T620502251017-69-1
Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist. Orexin receptor antagonist 4 shows IC50 of 4.27 nM and 295 nM for OX2R and OX1R, respectively.
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8-10 weeks
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ORN-0829 hydrate
T697152265899-50-9
ORN-0829 hydrate is a potent dual orexin 1 2 receptor antagonist for the treatment of insomnia.
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6-8 weeks
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Prostaglandin F2α dimethyl amine
PGF2α dimethyl amine, Dinoprost dimethyl amine
T8725467508-09-2
Prostaglandin F2α dimethyl amine, a Prostaglandin F2α derivative, acts as an antagonist for the Prostaglandin F receptor (FP) [1]. It blocks the cardiovascular responses induced by orexin and Arachidonic acid [2].
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10-14 weeks
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