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opc-14523 free base

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
OPC-14523 free base
VPI-013, VPI013, VPI 013, OPC-14523, OPC14523, OPC 14523
T28256145969-30-8In house
OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.
  • $1,520
6-8 weeks
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QTY
OPC-14523 dihydrochloride
OPC-14523 2hydrochloride
T62711LIn house
OPC-14523 dihydrochloride is the dihydrochloride form of the free base OPC-14523. OPC-14523 dihydrochloride is an orally active dual agonist of sigma receptors and 5-HT₁A receptors that also inhibits the 5-HT transporter, with IC₅₀ values of 47/56 nM for sigma receptors σ1/2, 5-HT₁A receptor IC₅₀ = 2.3 nM, and 5-HT transporter IC₅₀ = 80 nM. OPC-14523 dihydrochloride exhibits antidepressant-like activity. OPC-14523 dihydrochloride can be used in neuroscience research, including studies on antidepressants and neuroprotection.
  • $195
In Stock
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