ole1

YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM).

N-Methylphthalimide is a phthalimide that inhibits acetyl-coenzyme A synthetase.

Tert-Butyl5-bromo-1H-indole-1-carboxylate (N-Boc-5-bromoindole) is an indole derivative with therapeutic potential for pain, inflammation, and other conditions.

5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthetic compound. It has been used as a catalyst and as a tool in enzyme kinetic studies; it has also been used in studies of enzyme inhibition, as well as in drug receptor interaction studies.

Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein ligand via a linker to form PROTACIRAK4 degrader-1.

1H-Pyrrole-1-acetic acid, alpha-phenyl-, with CAS No. 105264-23-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-Pyrrole-1-acetic acid, alpha-phenyl- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.

Pomalidomide-PEG2-OH enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.

Pomalidomide-PEG3-OH enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.

5-Nitro-2-(pyridin-4-yl)-2,3-dihydro-1H-isoindole-1,3-dione ,with CAS No. 404896-26-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Nitro-2-(pyridin-4-yl)-2,3-dihydro-1H-isoindole-1,3-dione provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1H-Pyrido[3,4-b]indole-1,3 4(2H,9H)-trione is a useful organic compound for research related to life sciences and the catalog number is T125636.

Benzo[c][1,2]oxaborole-1,5(3H)-diol is a useful organic compound for research related to life sciences. The catalog number is T126262 and the CAS number is 1187190-70-0.

1H,2H,3H,4H,9H-pyrido[3,4-b]indole-1,3-dicarboxylic acid is a harmala alkaloid that is used in organic synthesis and biological experiments.

5-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione is a Thalidomide analog featuring a hydroxyl group, which serves as a versatile site for further derivatization. Thalidomide acts as an E3 ligase activator and facilitates the ubiquitination of specific proteins.

Trimosulfa is a combination of trimethoprim and sulfamethoxazole, an antibiotic combination. Sulfamethoxazole inhibits dihydropteroate synthase, while trimethoprim inhibits dihydrofolate reductase (dihydrofolate reductase), making it effective for mild to moderate bacterial infections against many Gram-negative and Gram-positive bacteria.

Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole. Riluzole is a glutamate antagonist with anticonvulsant activity, inhibiting GABA reuptake and used in ALS research.

rel-(3aR,4S,7R,7aS)-3a,4,7,7a-Tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione is a useful organic compound for research related to life sciences. The catalog number is T64449 and the CAS number is 6265-30-1.

exo-Hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione is a useful organic compound for research related to life sciences. The catalog number is T65551 and the CAS number is 14805-29-9.

Ethyl (4-(2-(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamido)ethyl)phenyl)sulfonylcarbamate is a useful organic compound for research related to life sciences. The catalog number is T65924 and the CAS number is 318515-70-7.

endo-Hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66460 and the CAS number is 28871-95-6.

1H-1,2,4-Triazole-1-carboximidamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67127 and the CAS number is 19503-26-5.

1H-Pyrazole-1-carboximidamide hydrochloride, catalog number T67134 and CAS number 4023-02-3, is a valuable organic compound for life sciences research.

Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.

TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.