notch4

BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-906024 prevents the activation of all four Notch receptors, and is active against Notch1, -2, -3 and -4 receptors. BMS-906024 prevents the activation of all four Notch receptors, with IC50s of 1.6, 0.7, 3.4 and 2.9 nM for Notch1, -2, -3 and -4 receptors, respectively.

The Anti-Mouse Notch4 Antibody (HMN4-14) is an IgG, κ antibody inhibitor derived from an American hamster, targeting the Notch4 protein in mice.

Anti-Notch4 Antibody is an antibody targeting Notch4. It can be used for developmental biology, bone metabolism, and oncology research.

Anti-Notch4 Antibody 2 is an antibody targeting Notch4. It can be used for developmental biology, bone metabolism, and oncology research.