nile red

Nile Red ((Nile Blue A oxazone)) is a lipophilic, environment-sensitive fluorescent dye. Highly hydrophobic, with fluorescence significantly enhanced in lipid-rich environments. Commonly used for specific staining of intracellular lipid droplets, with excitation/emission wavelengths of 559/635 nm.

2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe that can be incorporated into oligonucleotides as a nucleotide substitute. It serves as a DNA probe to detect polarity changes in the tumor microenvironment.

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derived from the Nile blue fluorophore, specifically designed for imaging thioredoxin (Trx) in live cells and in vivo, with excitation and emission wavelengths of 615 nm and 661 nm, respectively.

Nile Blue Methacrylamide, a Nile Blue-based nanosized pH sensor, enables simultaneous far-red and near-infrared live bioimaging [1].

SMCy5.5, an SMCy dye for lipid droplet labeling, exhibits a very high two-photon absorption cross-section. Unlike the well-known Nile Red, SMCy has narrow absorption and emission bands in visible light, facilitating multicolor imaging. SMCy is compatible with fixation, yielding high-quality 3D images of lipid droplets in cells and tissues. The high brightness of SMCy5.5 enables efficient tracking and imaging of lipid droplet exchange between adipocytes [1].