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nazartinib mesylate

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Nazartinib mesylate
EGF816 (mesylate)
T11156L1508250-72-3
Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222 min on EGFR(L858R 790M) mutant).
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1-2 weeks
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TargetMol
Nazartinib
NVS-816, EGF816
T35061508250-71-2
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
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TargetMol
Nazartinib S-enantiomer
EGF816 (S-enantiomer)
T111561508256-20-9
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
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8-10 weeks
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