n methylcytisine

1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).

N-Methylcytisine (Standard) is a reference standard for research and analysis in studies involving N-Methylcytisine. 1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).

DENV-IN-12 (Compound 6), a derivative of N-methylcytisine thio, effectively inhibits both DENV-1 and DENV-2. It demonstrates strong antiviral activity against DENV-2, with EC50 values between 0.002 and 0.005 μM across various cell lines [1].