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nω propyl l arginine

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Nω-Propyl-L-arginine
N-omega-Propyl-L-arginine,Nω-Propyl-L-arginine
T38786137361-05-8
Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM. It exhibits a remarkable 149-fold selectivity for nNOS over endothelial NOS (eNOS).
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Nω-Propyl-L-arginine hydrochloride
T380172321366-46-3
Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo. Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91 PMID:11404282 |Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869 PMID:9397167
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6-8 weeks
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