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Results for "
n,ndimethylsphingosine
" in TargetMol Product Catalog- Inhibitors & Agonists1
N,N-Dimethylsphingosine
N,N-Dimethylsphingosine (d18:1), DMS, D-erythro-N,N-dimethylsphingosin
T23045119567-63-4
N,N-Dimethylsphingosine, an endogenous metabolite, is a potent competitive sphingosine kinase (SphK) inhibitor that selectively inhibits sphingosine phosphorylation without affecting its N-acylation.DMS is elevated in models of neuropathic pain, and may mediate mechanical nociception by increasing the release of IL-1β and MCP-1.
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