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Results for "
msc2504877
" in TargetMol Product Catalog- Inhibitors & Agonists2
msc2504877
3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one
T600981460286-21-8
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4 6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
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Tankyrase-IN-5
T790261460285-69-1
Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2 with IC50 values of 2.3 nM and 7.9 nM, respectively [1].
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