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(3)
By Target- Ras
- Kras(2)
- NADPH(1)
- Others(1)
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By Target By ResearchField- Cancer(1)
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Results for "
mrtx1133
" in TargetMol Product Catalog.- Inhibitors & Agonists4
- MRTX1133 formicT37130MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells[1][2]. MRTX1133 demonstrates dose-dependent inhibition of the KRAS pathway tumor regression in G12D mutant tumor models[2]. [1]. Xiaolun Wang, et al.Kras g12d inhibitors.WO2021041671A1.[2]. KRAS G12D Inhibitor: MRTX1133. [(accessed on 22 April 2021)];2021 Available online.
- $1,046
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