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ml-289

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
ML289
VU0463597, ML 289
T230001382481-79-9
ML289 (VU0463597) is a potent, selective, and CNS-penetrant negative allosteric modulator of mGlu3 (IC50=0.66 μM), with over 15-fold selectivity compared to mGlu2 and no activity against mGlu5.
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6-8 weeks
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HWY-289
T86692908001-51-4
HWY-289, a semisynthetic protoberberine derivative, exhibits broad-spectrum and potent activities against phytopathogenic fungi, especially Botrytis cinerea (EC 50 = 1.34 μg mL). It alters the morphology of the mycelium and the internal structure of cells while decreasing ATP content, ATPase activities, and key enzyme activities in the TCA cycle [1].
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10-14 weeks
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