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ml-162

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | All_Pathways
ML162
T89701035072-16-2
ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity and selectively inhibits cell lines expressing mutant RAS oncogenes.
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TargetMol | Citations Cited
ML162-yne
T2037122883115-46-4
ML162-yne is an effective GPX4 inhibitor and affinity probe containing an alkyne group capable of click chemistry reactions with azide-containing molecules.
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Antibacterial agent 212
T209631
Antibacterial agent 212 (Compound 162) is an orally active antimicrobial with favorable pharmacokinetic properties, demonstrating a minimum inhibitory concentration (MIC) of 4 μg/mL against Pseudomonas aeruginosa T-2022-D2-048.
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Antibacterial agent 86
T74529
Compound A11 (Antibacterial agent 86) exhibits the highest bacteriostatic activity against methicillin-resistant S. aureus, with minimum inhibitory concentration (MIC) values reaching as low as 0.00191 μg/mL. This efficacy is 162 and 32 times greater than the commercial antibiotics tiamulin and retapamulin, respectively [1].
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