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Results for "
mk825
" in TargetMol Product Catalog- Inhibitors & Agonists3
SR1903 TFA
T696712351884-03-0
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated receptor γ (PPAR) but does not activate it. SR-1903 inhibits LPS-induced expression of triggering receptor expressed on myeloid cells 1 (TREM-1). It also inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1. SR-1903 reduces the severity of collagen-induced arthritis. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity.
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MK-825 hydrochloride hemi-ethylacetate
MK825 HCl hemi-ethylacetate, MK-825 HCl hemi-ethylacetate, MK 825 HCl hemi-ethylacetate
T20204823298-10-4
MK-825 hydrochloride hemiacetate is a CETP inhibitor.
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