methyl jasmonate

Methyl jasmonate ((-)-Methyl jasmonate) is a hormone involved in plant signaling, inducing oxidative stress and accumulation of secondary metabolites in plant cells and organ cultures, and regulating the biosynthesis of other plant hormones. Methyl jasmonate induces plant defense responses against Andean lupin insects. Methyl jasmonate has anti-inflammatory activity.

Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester) induces the synthesis of proteinase inhibitors in plant leaves, suppresses proliferation, and induces apoptosis in cancer cells. It inhibits hexokinase bound to mitochondria, disrupting mitochondrial hexokinase activity to selectively target and kill cancer cells. Derivatives of Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate also exhibit potential as anti-inflammatory agents, and the compound has been primarily detected in urine.