menaquinone 4

Menaquinone 4-d7 (Mixture of cis-trans isomers) is a deuterated compound of Menaquinone 4 (Mixture of cis-trans isomers).

Menaquinone-4 (Vitamin K2) is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.

Menaquinone-4 (Standard) is a reference standard for research and analysis in studies involving Menaquinone-4. Menaquinone-4 (Vitamin K2) is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.

Menaquinone-4-[13C6] (Standard) is a reference standard of Menaquinone-4-[13C6] intended for quantitative analysis, quality control, and related biochemical research applications.

Menaquinone-4-[d7] 2,3-Epoxide (Standard) is a reference standard of Menaquinone-4-[d7] 2,3-Epoxide intended for quantitative analysis, quality control, and related biochemical research applications.

Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin inhibits growth of B. subtilis (MIC = 0.05 μg/ml) and induces efflux of potassium ions from B. subtilis without affecting Na+/K+-ATPase activity. It decreases the synthesis of protein, RNA, and DNA in B. subtilis when used at a concentration of 0.05 μg/ml. It inhibits the growth of B. halodurans (MIC = 10 ng/ml) and inhibits the futalosine pathway of menaquinone synthesis in B. halodurans. Boromycin (3.4 nM) reverses bleomycin-induced cell cycle arrest at the G2 phase in Jurkat cells. It inhibits replication of the HIV-1 strains LAV-1 and RF and the HIV-2 strain LAV-2 in MT-4 cells (IC50s = 0.008, 0.11, and 0.007 μM, respectively). It also inhibits replication of a clinical isolate of HIV-1, strain KK-1, in MT-4 cells and peripheral blood mononuclear cells (PBMCs; IC50s = 0.14 and <0.1 μM, respectively).

MK7-d7 is a deuterated compound of MK7. MK7 has a CAS number of 2124-57-4. Menaquinone-7 is a vitamin K2 analog, is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins.