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By Target- Gamma-secretase
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Results for "
mdl28815
" in TargetMol Product Catalog- Inhibitors & Agonists2
CIA-1 hcl(452087-38-6 Free base)
T715341049691-47-5
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.
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