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Results for "
mcla hydrochloride
" in TargetMol Product Catalog.- Inhibitory Antibodies1
- Dye Reagents1
- MCLA hydrochlorideT19024128322-44-1MCLA hydrochloride is a monoclonal antibody that binds EGFR and LGR5 with Kd values of 0.22 nM and 0.86 nM, respectively. MCLA hydrochloride induces EGFR signaling blockade and receptor degradation in LGR5-positive cancer cells. MCLA hydrochloride is utilized in oncology research involving solid tumors, including head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC), and serves as a molecular tool for investigating EGFR- and LGR5-associated signaling pathways and tumor biology.
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