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By Target- Melanocortin Receptor
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Results for "
mc2r
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Recombinant Protein1
Dersimelagon
MT-7117
T253101835256-48-8
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14, and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m), and rat (r) MC1R, respectively. Dersimelagon exhibits good affinity for hMC1R and hMC4R, with Ki values of 2.26 and 32.9 nM, respectively. Dersimelagon can be used in the study of skin pigmentation[1].
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Atumelnant
CRN 04894, CRN04894
T860912392970-97-5
Atumelnant (CRN04894) is a selective and potent MC2R antagonist that inhibits ACTH-stimulated corticosterone secretion in a dose-dependent manner for the study of congenital adrenocortical hyperplasia (CAH) and Cushing's disease (CD).
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GPS1573
T888802445822-54-6
GPS1573 is a non-competitive antagonist of the melanocortin 2 receptor (MC2R) that blocks the ACTH-stimulated activity of MC2R in a dose-dependent manner (IC50=66 nM). Due to its high selectivity in antagonizing MC2R, GPS1573 is utilized for research in Cushings disease.
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